In the history of production capsules, Gelatin is most often used for capsule material due to its wide range of sources. It has stable physical and chemical properties and excellent processing properties which are widely used in food, medicine, and health products.
The gelatin is sourced from the bones and skins of animals such as cattle and pigs. The animal origin materials risks are attracting attention since the Mad Cow Disease and Foot-and-Mouth Disease.
Hydroxypropyl methylcellulose (HPMC) is a semisynthetic, viscoelastic polymer, it is a cellulose ether.Hydroxypropylmethyl cellulose (HPMC) can be dissolved into some organic solvents and also in water-organic solvent mixed solvents. it does not have a gelation property when heated. HPMC is a is non-toxic to humans the raw material from cotton and wood.
HPMC is derived from cotton and wood pulp, and does not come into contact with any animal-derived materials during the production process. Its material and production process are approved by the Jewish, Islamic and Vegetarian Associations, and can meet the needs and acceptance of people with various religions and eating habits.
HPMC as a raw material for capsules and tablets has the following advantages:
1) Low moisture content, not easy to absorb external moisture;
2) The toughness is high, and the product is not easily broken;
3) High chemical stability, not easy to react with pharmaceutical ingredients;
4) Good coating performance;