Hydroxypropyl Methylcellulose HPMC E3
| Other Name | Hydroxypropyl Methylcellulose |
|---|---|
| CAS No | 9004-65-3 |
| H.S Code | 39129090 |
| Packing | 25KG fiber drums |
| MOQ | 200KGS |
Product Introduction
HPMC E3 is a low-viscosity grade of Hydroxypropyl Methylcellulose widely used in pharmaceutical applications. It is a non-ionic, water-soluble cellulose ether derived from natural polymer cellulose, offering excellent film-forming, binding, and stabilizing properties.
Designed to meet strict pharmaceutical standards, HPMC E3 is highly suitable for use in solid dosage forms, liquid formulations, and coating systems.
Typical specifications
| Items | Specification |
|---|---|
| Methoxy Content | 28.0% - 30.0% |
| Hydroxypropyl Content | 7% - 12% |
| PH | 5 - 8 |
| Loss on drying | 5% max |
| Heavy metal | 10 ppm max |
| Arsenic | 2 ppm max |
| Apparent Viscosity | 2 - 4 (mPa.s) |
| Residue On Ignition | 1.5% max |
| Total Bacterium | 1000/g max |
| Mold | 100/g max |
Applications
- Binder in Tablets: It is commonly used as a binder in tablet formulations, helping to hold the ingredients together and ensuring uniformity in tablet weight and strength.
- Controlled Release: HPMC E3 is employed in controlled-release formulations, allowing for a gradual release of active pharmaceutical ingredients (APIs) over time, which can improve therapeutic efficacy and patient compliance.
- Thickening Agent: In liquid formulations, such as suspensions and gels, HPMC E3 acts as a thickening agent, improving viscosity and stability.
- Film Coating: It can be used for film coating of tablets, providing a protective layer that can improve stability, mask taste, and enhance appearance.
- Stabilizer in Emulsions: HPMC E3 serves as a stabilizer in emulsions, helping to maintain the dispersion of ingredients in topical formulations.
- Matrix Formulation: In extended-release tablets, it forms a gel matrix that controls the release of drugs, allowing for sustained therapeutic effects.
- Excipient for Hydrophilic Drugs: It is often used as an excipient for hydrophilic drugs, helping to improve solubility and bioavailability.
Packaging & Storage
HPMC is available in 25kg fiber drums, 20KG cartons, Poly lined with pallets.