Hydroxypropyl Methylcellulose HPMC E4M
| Other Name | Hydroxypropyl Methylcellulose |
|---|---|
| CAS No | 9004-65-3 |
| H.S Code | 39129090 |
| Packing | 25KG fiber drums |
| MOQ | 200KGS |
Hydroxypropyl Methylcellulose (HPMC E4M) – Pharmaceutical Grade
HPMC E4M is a high-viscosity grade of Hydroxypropyl Methylcellulose, specifically designed for advanced pharmaceutical formulations requiring strong gel formation, high viscosity, and controlled drug release. As a non-ionic, water-soluble cellulose ether derived from natural cellulose, HPMC E4M is widely used in sustained-release dosage forms and matrix systems.
With significantly higher viscosity compared to lower grades such as E3, E6, and E50, HPMC E4M provides superior gel strength and extended release control, making it ideal for hydrophilic matrix tablet formulations.
Typical specifications
| Items | Specification |
|---|---|
| Methoxy Content | 28.0% - 30.0% |
| Hydroxypropyl Content | 7% - 12% |
| PH | 5 - 8 |
| Loss on drying | 5% max |
| Apparent Viscosity | 3,000 – 5,600 mPa·s |
| Residue On Ignition | 1.5% max |
| Total Bacterium | 1000/g max |
| Mold | 100/g max |
Applications
- Binder in Tablets: Helps maintain tablet integrity and uniformity.
- Film Coating: Used for tablet film coating to protect and mask taste.
- Controlled Release: Useful in formulations requiring modified release profiles.
Packaging & Storage
HPMC is available in 25kg fiber drums, 20KG cartons, Poly lined with pallets.