Hydroxypropyl Methylcellulose HPMC E5
| Other Name | Hydroxypropyl Methylcellulose |
|---|---|
| CAS No | 9004-65-3 |
| H.S Code | 39129090 |
| Packing | 25KG fiber drums |
| MOQ | 200KGS |
Reliable Bulk Supply of HPMC 2910 E5 for Pharmaceutical Applications
HPMC E5 is a cellulose-based polymer commonly used in film coating, wet granulation, and hard capsule production. It is nearly insoluble in hot water, acetone, anhydrous ethanol, and toluene, but dissolves in cold water to form a colloidal solution. HPMC E5 is classified as E type 2910, with an average methoxyl group content of 29% and an average hydroxypropyl group content of 10%. The JRS Pharma hypromellose product line offers a range of E grades, varying from low to high viscosity.
Typical specifications
| Items | Specification |
|---|---|
| Methoxy Content | 28.0% - 30.0% |
| Hydroxypropyl Content | 7% - 12% |
| PH | 5 - 8 |
| Loss on drying | 5% max |
| Heavy metal | 10 ppm max |
| Arsenic | 2 ppm max |
| Apparent Viscosity | 3 - 6 (mPa.s) |
| Residue On Ignition | 1.5% max |
| Total Bacterium | 1000/g max |
| Mold | 100/g max |
Applications
- Binder in Tablets: It is commonly used as a binder in tablet formulations, helping to hold the ingredients together and ensuring uniformity in tablet weight and strength.
- Controlled Release: HPMC E5 is employed in controlled-release formulations, allowing for a gradual release of active pharmaceutical ingredients (APIs) over time, which can improve therapeutic efficacy and patient compliance.
- Thickening Agent: In liquid formulations, such as suspensions and gels, HPMC E5 acts as a thickening agent, improving viscosity and stability.
- Film Coating: It can be used for film coating of tablets, providing a protective layer that can improve stability, mask taste, and enhance appearance.
- Stabilizer in Emulsions: HPMC E5 serves as a stabilizer in emulsions, helping to maintain the dispersion of ingredients in topical formulations.
- Matrix Formulation: In extended-release tablets, it forms a gel matrix that controls the release of drugs, allowing for sustained therapeutic effects.
- Excipient for Hydrophilic Drugs: It is often used as an excipient for hydrophilic drugs, helping to improve solubility and bioavailability.
Packaging & Storage
HPMC is available in 25kg fiber drums, 20KG cartons, Poly lined with pallets.